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Index > Protein center > Pfkfb4(Gene name) > Rat
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  • Pfkfb4 (Gene name),
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (Protein name ),  F264_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Pfkfb4;
    Protein name:
    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4(6PF-2-K/Fru-2,6-P2ase 4;PFK/FBPase 4);
    Alternative:
    6PF-2-K/Fru-2,6-P2ase testis-type isozyme;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Synthesis and degradation of fructose 2,6-bisphosphate.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    469
    Sequence:
    50:
    MASPRELTQN | PLKKIWMPYS | NGRPALHASQ | RGVCMTNCPT | LIVMVGLPAR | 
    100:
    GKTYISKKLT | RYLNWIGVPT | REFNVGQYRR | DMVKTYKSFE | FFLPDNEEGL | 
    150:
    KIRKQCALAA | LNDVRKFLSE | EGGHVAVFDA | TNTTRERRAM | IFNFGEQNGY | 
    200:
    KTFFVESICV | DPEVIAANIV | QVKLGSPDYV | NRDSDEATED | FMRRIECYEN | 
    250:
    SYESLDEEQD | RDLSYIKIMD | VGQSYVVNRV | ADHIQSRIVY | YLMNIHVTPR | 
    300:
    SIYLCRHGES | ELNLKGRIGG | DPGLSPRGRE | FSKHLAQFIS | DQNIKDLKVW | 
    350:
    TSQMKRTIQT | AEALSVPYEQ | WKVLNEIDAG | VCEEMTYEEI | QDHYPLEFAL | 
    400:
    RDQDKYRYRY | PKGESYEDLV | QRLEPVIMEL | ERQENVLVIC | HQAVMRCLLA | 
    450:
    YFLDKAAEEL | PYLKCPLHTV | LKLTPVAYGC | KVESIFLNVA | AVNTHRDRPQ | 
    469:
    NVDISRPSEE | ALVTVPAHQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    E10217r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    U10217r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Cat.:
    P10217Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Monoclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Monoclonal Antibody for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Rat 6PF-2-K/Fru-2,6-P2ase 4
    Protein for Rat 6PF-2-K/Fru-2,6-P2ase 4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase."
      Sakata J. , Abe Y. , Uyeda K.
      J. Biol. Chem.266:15764-15770(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      "The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies."
      Hasemann C.A. , Istvan E.S. , Uyeda K. , Deisenhofer J.
      Structure4:1017-1029(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH ATP ANALOG
      tissue: Testis.
    3. 3.
      "Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities."
      Yuen M.H. , Mizuguchi H. , Lee Y.H. , Cook P.F. , Uyeda K. , Hasemann C.A.
      J. Biol. Chem.274:2176-2184(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF MUTANT ALA-257 IN COMPLEX WITH ATP ANALOG; FRUCTOSE 6-PHOSPHATE AND PHOSPHATE ION;SUBUNIT;ACTIVE SITE
      tissue: Testis.
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